著者

Imai Hajime Era Seiichi Hayashi Tomoya NEGAWA Tsuneo MATSUYAMA Yukie OKIHARA Kiyoshi NAKATSUMA Akira YAMADA Hideo

出版者

日本運動生理学会

雑誌

Advances in exercise and sports physiology (ISSN:13403141)

巻号頁・発行日

vol.11, no.3, pp.109-113, 2005-11

被引用文献数

3

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Human serum albumin (HSA) is a mixture of human mercapt-(HMA, reduced form) and nonmercaptalbumin (HNA, oxidized form), and is known to be one of the major extracellular scavengers for reactive oxygen species. Using a high-performance liquid chromatographic (HPLC) system with an ES-502N column, we studied the redox state of HSA for male Japanese fencing ("kendo") athletes (n=11) before and after an intense kendo training camp for 4 days. In order to clarify the antioxidative effect of propolis supplementation on the HSA redox state during camp, subjects were divided into two groups (placebo group, n=5; propolis group, n=6). A double blind test was utilized. The propolis used in this study was a product of Brazil (daily amount of propolis was 787.5mg). During camp, the observed decrease in the mean values of [HMA/(HMA+HNA)] (f^^-(HMA)) in the placebo group was significant (76.8±1.66% before and 63.0±2.29% after camp; P<0.05). Similarly, those values for the propolis group were also significant (77.0±0.94% before and 70.5±1.51% after camp; P<0.05). For the propolis group, however, the degree of the decrease in the f^^-(HMA) value was significantly small compared with that of the placebo group (P<0.05). In addition, the change in the f^^-(HMA) value of the propolis group during the training camp was roughly within the normal range of that of healthy male subjects previously reported (73.2±2.34%). These findings suggest that propolis may be an effective supplement to improve the redox state of HSA for kendo athletes in repetitive and highly intensive training camps.