- 著者
- Yasuhiko Matsumoto Kazuhisa Sekimizu
- 出版者
- バイオ&ソーシャル・サイエンス推進国際研究交流会
- 雑誌
- Drug Discoveries & Therapeutics (ISSN:18817831)
- 巻号頁・発行日
- vol.10, no.1, pp.14-18, 2016 (Released:2016-03-12)
- 参考文献数
- 26
- 被引用文献数
- 6
Silkworm shows hyperglycemia after intake of diet containing large amount of glucose. The hyperglycemic silkworm model is useful for evaluation of anti-diabetic drugs. A hot water extract of Rehmanniae Radix, an herbal medicine, showed hypoglycemic effect against the hyperglycemic silkworms. This method is applicable for quick and simple evaluation of the hypoglycemic activities of different batches of Rehmanniae Radix. Our findings suggest that silkworms have a lot of merit as experimental animals for evaluation of various herbal medicines.