著者
Yi ZHANG Hisamine KOBAYASHI Kazunori MAWATARI Juichi SATO Gustavo BAJOTTO Yasuyuki KITAURA Yoshiharu SHIMOMURA
出版者
Center for Academic Publications Japan
雑誌
Journal of Nutritional Science and Vitaminology (ISSN:03014800)
巻号頁・発行日
vol.57, no.1, pp.114-117, 2011 (Released:2011-04-22)
参考文献数
14
被引用文献数
19 28 8

The present study was conducted to examine alterations in the concentrations of plasma free amino acids, glucose, insulin, free fatty acids (FFAs), and urea nitrogen induced by branched-chain amino acid (BCAA) supplementation in young men. Overnight-fasted subjects ingested drinks containing 1 or 5 g of a BCAA mixture (weight ratio of 1 : 2.3 : 1.2 for isoleucine : leucine : valine), and blood was intermittently collected for 3 h after ingestion. Ingestion of the BCAA mixture resulted in significant increases in the plasma concentrations of individual BCAAs, corresponding to the amounts of amino acids ingested. On the other hand, plasma concentrations of methionine and aromatic amino acids tended to decrease in the trial with 5 g BCAAs, suggesting that BCAA ingestion affects the metabolism of these amino acids. The ingestion of BCAAs temporarily increased plasma insulin levels and affected plasma concentrations of FFAs, but had almost no effect on glucose or urea nitrogen.
著者
Yoshiharu SHIMOMURA Yasuyuki KITAURA Yoshihiro KADOTA Takuya ISHIKAWA Yusuke KONDO Minjun XU Miki OTA Yukako MORISHITA Jussiaea V. BARIUAN Hongmin ZHEN
出版者
Center for Academic Publications Japan
雑誌
Journal of Nutritional Science and Vitaminology (ISSN:03014800)
巻号頁・発行日
vol.61, no.Supplement, pp.S112-S114, 2015 (Released:2015-11-24)
参考文献数
16
被引用文献数
13 20

Branched-chain amino acids (BCAAs) are essential amino acids for humans and are major building blocks of proteins. Recent studies indicate that BCAAs act not only as components of proteins, but also as nutrasignals. In this review, we summarize the findings of recent studies investigating the physiological functions of BCAAs in the regulation of protein and glucose metabolism and brain function.