著者
Ogasawara Yui Murai Yuta Sakihama Yasuko Hashidoko Yasuyuki Hashimoto Makoto
出版者
Japan Institute of Heterocyclic Chemistry
雑誌
Heterocycles (ISSN:03855414)
巻号頁・発行日
vol.86, no.1, pp.735-743, 2012-12-31
被引用文献数
1

The click reaction is one of the latest techniques for the chemical modification of bioactive compounds. Chemical modifications of α-amino acid side chains are gaining significance as useful and important tools for biochemical research. Biotinylation at side chain of propargylglycine using click reaction was examined. The detail quantitative analysis of Cu(I) concentration are performed to proceed the click reaction effectively.