著者

松山 圭子

出版者

青森公立大学

雑誌

青森公立大学紀要 (ISSN:13419412)

巻号頁・発行日

vol.9, no.1, pp.47-61, 2003-09-30

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Since Oct.15^<th>, 2002, newspapers have reported a number of deaths related to the adverse reaction to anti-lung cancer drug, "Irresa"(generic name: gefitinib, Asterazeneca). The reports described this drug-induced disaster as a result of irresponsibility of Japanese government, pharmaceutical company and medical professionals. However before the Oct.15-article, the newspapers had covered Irresa as a notable drug that has molecular targeting action pinpointing cancer growth mechanism. For a critical analysis of this new drug, more of the clinical evidence is needed than pharmacological mechanism. And yet pharmacological knowledge based analogy and metaphor is often used in clinical doctors' stories or narratives. And mass media make report without critically examining the medical knowledge. I would like to argue this drug-induced disaster as "failure of knowledge".

著者

佐藤 和弘

出版者

青森公立大学

雑誌

青森公立大学紀要 (ISSN:13419412)

巻号頁・発行日

vol.10, no.1, pp.13-20, 2004-09-30

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The 1/f (f inverse) fluctuation is observed in nature quite generally. It is found that the 1/f fluctuation influences the human brain, and strongly settles the central nerve system. However the mechanism of this phenomenon is unknown as yet. This paper suggests that the interaction between the brain stem and the limbic system is responsible for this mechanism. The 1/f fluctuation is detected by the A10 nuclei (a pair of small neural network) in the brain stem, and the excited A10 stimulates the amygdaloid body in the limbic system. Then the amygdaloid body exhibits an emotional response (satisfaction) instinctively. When the 1/f fluctuation vanishes, the brain will recognize that a certain kind of dangerous situation progresses inside or outside of the body.

著者

佐藤 和弘

出版者

青森公立大学

雑誌

青森公立大学紀要 (ISSN:13419412)

巻号頁・発行日

vol.8, no.1, pp.12-34, 2002-09-30

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This paper discusses early pioneering works of Torahiko Terada (1878〜1935) on Life Sciences.

著者

羽矢 辰夫

出版者

青森公立大学

雑誌

青森公立大学紀要 (ISSN:13419412)

巻号頁・発行日

vol.18, no.1, pp.21-30, 2013-03