著者
Tomoaki Murakami Yoko Horibata Shigeru Tateno Yasutaka Kawasoe Koichiro Niwa
出版者
一般社団法人 日本血管不全学会
雑誌
Vascular Failure (ISSN:24324477)
巻号頁・発行日
vol.4, no.2, pp.39-45, 2021-08-31 (Released:2021-09-08)
参考文献数
20
被引用文献数
1

Background:We previously reported enhanced pressure wave reflection in adult patients with congenital heart disease, which can result in high systolic blood pressure. Although hypertension could cause significant damage to vulnerable systemic ventricles, few studies have reported on blood pressure in adults with congenital heart disease thus far. The purpose of this study was to investigate the incidence and risk factors associated with hypertension in adult patients with congenital heart disease. Methods and Results:One-hundred and thirty-one adults with congenital heart disease were enrolled in this study. Brachial blood pressure was measured using an HEM-9000AI system (Omron Healthcare Co., Ltd., Kyoto, Japan). Patients with systolic/diastolic blood pressure ≥140/90 mmHg or those taking medication for hypertension were defined as hypertension. A systolic blood pressure ≥ +2 SD of systolic blood pressure in the age- and sex-matched general population was defined as high systolic blood pressure. The patients were aged 37.0 ± 15.0 years. Hypertension was observed in sixteen patients (16%), and logistic regression analysis revealed that the determinant of hypertension was age (years) (odds ratio [OR], 1.078; 95% confidence interval [CI], 1.029-1.129; p = 0.001). High systolic blood pressure was observed in twenty patients (20%). Logistic regression analysis revealed that the determinants of high systolic blood pressure were age (years) (OR, 1.072; 95%CI, 1.020-1.126; p = 0.016) and body mass index (kg/m2) (OR, 1.261; 95% CI, 1.054-1.508; p = 0.011). The body mass index in young patients (≤ 30 years) with high systolic blood pressure was remarkably high (31.2 ± 3.0 kg/m2). Conclusions:The incidence of high systolic blood pressure is high in adult patients with congenital heart disease. High systolic blood pressure is common in older patients and is associated with a high body mass index in young patients.
著者
Tatsuya Maruhashi Masahiko Ogawa Yasuo Fukunaga Daisaku Kitaura Masato Kajikawa Shinji Kishimoto Yuji Takaeko Takayuki Yamaji Takahiro Harada Yu Hashimoto Yiming Han Aya Mizobuchi Farina Mohamad Yusoff Kazuaki Chayama Ayumu Nakashima Chikara Goto Kenichi Yoshimura Yukiko Nakano Yukihito Higashi
出版者
Japan Society for Vascular Failure
雑誌
Vascular Failure (ISSN:24324477)
巻号頁・発行日
vol.6, no.1, pp.14-19, 2022-12-25 (Released:2023-02-14)
参考文献数
15

Background: Sleep apnea is an independent risk factor for motor vehicle accidents. We investigated the prevalence of sleep-disordered breathing (SDB) among commercial motor vehicle drivers in a transport company. Methods: Among 355 drivers in a transport company, 345 commercial motor vehicle drivers (mean age: 47.0±8.8 years, range: 21-71 years) underwent unattended out-of-center sleep testing using a type IV portable sleep monitor between September 2019 and November 2019.Results: The prevalence of oxygen desaturation index 3% (ODI3) score ≥15 was 17.7%. The prevalence of moderate-to-severe SDB, defined as respiratory event index (REI) score ≥15, was 31.9%. The prevalence of Epworth Sleepiness Scale (ESS) score ≥11 was 15.3%. There was no significant correlation between the ESS score and ODI3 (ρ=−0.05, P=0.40) or REI (ρ=−0.03, P=0.65) score. Multivariate analysis revealed that age (odds ratio [OR]: 1.05, 95% confidence interval [CI]: 1.02-1.09, P=0.002), body mass index (OR: 1.14, 95% CI: 1.05-1.23, P<0.001), and daily alcohol intake (OR: 1.98, 95% CI: 1.10-3.55, P=0.02) were significantly associated with moderate-to-severe SDB in drivers. The ESS score was not significantly associated with moderate-to-severe SDB (OR: 0.98, 95% CI: 0.93-1.05, P=0.70).Conclusions: Objective screening tests for sleep apnea such as unattended out-of-center sleep testing may be necessary to improve the health and safety of commercial motor vehicle drivers, especially middle-aged obese male drivers having daily alcohol intake.