- 著者
- Takebayashi Takashi Takahashi Kayoko Amano Satoru Uchiyama Yuki Gosho Masahiko Domen Kazuhisa Hachisuka Kenji 五所 正彦
- 出版者
- Frontiers
- 雑誌
- Frontiers in Neurology (ISSN:16642295)
- 巻号頁・発行日
- no.9, 2018-08
Background: Stroke patients experience chronic hemiparesis in their upper extremities leaving negative effects on quality of life. Robotic therapy is one method to recover arm function, but its research is still in its infancy. Research questions of this study is to investigate how to maximize the benefit of robotic therapy using ReoGo-J for arm hemiplegia in chronic stroke patients.Methods: Design of this study is a multi-center parallel group trial following the prospective, randomized, open-label, blinded endpoint (PROBE) study model. Participants and setting will be 120 chronic stroke patients (over 6 months post-stroke) will be randomly allocated to three different rehabilitation protocols. In this study, the control group will receive 20 min of standard rehabilitation (conventional occupational therapy) and 40 min of self-training (i.e., sanding, placing and stretching). The robotic therapy group will receive 20 min of standard rehabilitation and 40 min of robotic therapy using ReoGo®-J device. The combined therapy group will receive 40 min of robotic therapy and 20 min of constraint-induced movement therapy (protocol to improve upper-limb use in ADL suggests). This study employs the Fugl-Meyer Assessment upper-limb score (primary outcome), other arm function measures and the Stroke Impact Scale score will be measured at baseline, 5 and 10 weeks of the treatment phase. In analysis of this study, we use the mixed effects model for repeated measures to compare changes in outcomes between groups at 5 and 10 Weeks. The registration number of this study is UMIN000022509.Conclusions: This study is a feasible, multi-site randomized controlled trial to examine our hypothesis that combined training protocol could maximize the benefit of robotic therapy and best effective therapeutic strategy for patients with upper-limb hemiparesis.
- 著者
- Kubota Takaaki Kobayashi Tohru Nunoura Takuro Maruyama Fumito Deguchi Shigeru
- 出版者
- Frontiers
- 雑誌
- Frontiers in Microbiology (ISSN:1664302X)
- 巻号頁・発行日
- vol.7, 2016-04-19
- 被引用文献数
- 28
深海にひろがる鏡の向こうの微生物世界-Dアミノ酸を好む深海微生物を発見-. 京都大学プレスリリース. 2016-04-27.
- 著者
- Ogihara Yuji Uchida Yukiko
- 出版者
- Frontiers
- 雑誌
- Frontiers in psychology (ISSN:16641078)
- 巻号頁・発行日
- vol.5, 2014-03-05
- 被引用文献数
- 70
個人主義的な人は、親しい友人の数が少なく幸福感が低い -日本社会の個人主義化がもたらす負の側面を示唆-. 京都大学プレスリリース. 2014-03-19.