髙村 (赤司) 祥子
- 一般社団法人 日本エンドトキシン・自然免疫研究会
- エンドトキシン・自然免疫研究 (ISSN:24341177)
- vol.22, pp.79-82, 2019 (Released:2019-11-06)
The bee venom (BV) is the secretion which is produced by a needle device for protection the bee from an enemy. However, BV has been applied to the folk medicine for various diseases because it is included many enzymes which are containing anti-inflammatory or anti-cancer action. Above all, Phospholipase A2 (PLA2) is a hydrolytic enzyme which cleaves membrane phospholipids, and in bee venom occupying up to 12%. PLA2 has been analyzed in greatest detail. This mini review sets out the latest scientific evidence concerning the therapeutic effects of PLA2 in the context of diseases and provides a detailed description of the mechanisms.