著者
Saki KONDO Takuya KARASAWA Ayumi FUKAZAWA Atsuko KOIKE Momoko TSUTSUI Shin TERADA
出版者
Center for Academic Publications Japan
雑誌
Journal of Nutritional Science and Vitaminology (ISSN:03014800)
巻号頁・発行日
vol.68, no.2, pp.97-103, 2022-04-30 (Released:2022-04-30)
参考文献数
28
被引用文献数
1

We previously reported that the combination of a very high-carbohydrate diet and endurance training increased glucose transporter 4 and glycogen concentration in skeletal muscle. However, it remains unclear whether they also affect the digestive and absorptive capacity in the pancreas and small intestine, which are suggested to be rate-limiting steps in the delivery of exogenous carbohydrates to skeletal muscle and muscle glycogen synthesis. Thus, we aimed to evaluate the effects of a very high-carbohydrate diet and endurance training on pancreatic amylase activity and intestinal glucose transporters in rats and to examine the relationship between these adaptations and their influence on muscle glycogen concentration. Male Sprague–Dawley rats (n=29) were fed a high-carbohydrate diet (59% carbohydrate) or a very high-carbohydrate diet (76% carbohydrate) for 4 wk. Half of the rats in each dietary group were subjected to 6-h swimming exercise training (two 3-h sessions separated by 45 min of rest) for 4 wk. Although there was no significant effect of diet or endurance training on sodium-dependent glucose transporter 1 and glucose transporter 2 contents in the intestine, the rats fed a very high-carbohydrate diet in combination with endurance training had substantially higher pancreatic amylase activity and muscle glycogen concentration. Furthermore, there was a positive correlation between pancreatic amylase activity and muscle glycogen concentration (r=0.599, p=0.001). In conclusion, intake of a very high-carbohydrate diet and endurance training synergistically elevated carbohydrate digestive capacity, which partially accounted for the higher muscle glycogen accumulation.

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今年の初読みは、国際学会で初めてお会いした日本人研究者のラットでの研究。 https://t.co/ksjPzFo3l0 今までは動物研究を読むことはほとんどなかったですが、仮説を立てたり研究デザインを学んだりするのに、今後は読む機会が増えるかも…? 今年もたくさん読むのだ。 そして今年からは書くのだ!
Effects of a Very High-Carbohydrate Diet and Endurance Exercise Training on Pancreatic Amylase Activity and Intestinal Glucose Transporter Content in Rats (open access) https://t.co/19zDuMJAQR #nutrition #diet #exercise #muscle #strength #lift #GetStrong #cardio #hiit

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