Very interesting study showing that Zinc deficiency may release Zn-dependent block of Cav3.2 #calcium #ionchannels thus leading to nociceptive hypersensitivity! https://t.co/JNbJPOCyuH
Interesting example of #drugrepurposing for #pain therapeutic - #Bepridil (antiarrhythmic & antianginal) and #Pimozide (antipsychotic) alleviate visceral pain in mice partly via inhibition of T-type #calcium #ionchannels ➡️ https://t.co/kKPQLydghE https://t.co/rB1FDo9MBq