Note this case study: -52-yo woman w/ recent stroke & underlying cerebral microangiopathy w/ ⬆️ risk of ICH -Family history of brain bleed (father, paternal uncle died) -Daily aspirin 100 mg -7 days after adding NK 400 mg, diagnosed w/ cerebral hemorrhage https://t.co/V38I5o4h22

BISOPROLOL: Bisoprolol not studied with nattokinase so cannot fully assess risk. However, this trial found that bisoprolol was associated with sig DECREASED bleeding risk (~50%) when taken with direct oral anticoagulants (aOR, 0.51; 95% CI, 0.33-0.80). https://t.co/vUw9TS54Ql