著者

北所 健悟 三木 邦夫

出版者

The Crystallographic Society of Japan

雑誌

日本結晶学会誌 (ISSN:03694585)

巻号頁・発行日

vol.40, no.5, pp.322-328, 1998-10-28

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The crystal structure of 8-HDF type photolyase from <I>Anacystis nidulans</I> showed the similarity of the backbone structure with MTHF type <I>E. coli</I> photolyase but completely different binding site of the light-harvesting cofactor. This is a first example that homologous primary and tertiary structures in closely related proteins recognize two different types of cofactors at different binding-sites. The structure and function of photolyase and its cofactor recoginition are reviewed and discussed.