著者

松坂 尚典 SAKAMOTO HIDEKI SATO ITARU SHINAGAWA KUNIHIRO KOBAYASHI HARUO NISHIMURA YOSHIKAZU

出版者

日本放射線影響学会

雑誌

Journal of radiation research (ISSN:04493060)

巻号頁・発行日

vol.36, no.3, pp.196-202, 1995-09

被引用文献数

2

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Whole-body retention and fetal uptake of ^<65>5Zn under a Zn-deficient diet were studied in pregnant mice in the late gestational stage after a single oral administration of ^<65>Zn. Whole-body retentions were much greater in mice given a Zn-deficient diet than in those given a Zn-normal diet. Accordingly, the amount of ^<65>Zn transmitted to the offspring in utero was greater in the Zn-deficient diet group. In another experiment, fetal uptake of ^<65>Zn in dams on gestation day 17 was examined over a period of 24 hr after a single intravenous administration of ^<65>Zn to the Zn-deficient and Zn-normal animals. There was no major difference in fetal uptake between the two groups, indicative that approximately a similar proportion of the ^<65>Zn retained in the maternal body was transmitted to the in utero offspring in both groups.