著者

梅澤 勲 野澤 雅子 南雲 紳史 秋田 弘幸

出版者

公益社団法人日本薬学会

雑誌

Chemical & pharmaceutical bulletin (ISSN:00092363)

巻号頁・発行日

vol.43, no.7, pp.1111-1118, 1995-07-15

被引用文献数

1

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Three kinds of oudemansin X, (-)-1,(+)-1 and (±)-1,were totally synthesized. The key point in the present chiral synthesis was the enantioselective acetylation of the racemic alcohols, (±)-5 and (±)-8,using lipase in an organic solvent. The synthetic (-)-1 was found to exhibit strong antifungal activity against several molds and yeasts.