著者
中原 雄二
出版者
公益社団法人 日本薬学会
雑誌
衛生化学 (ISSN:0013273X)
巻号頁・発行日
vol.36, no.2, pp.100-108, 1990-04-28 (Released:2008-05-30)
参考文献数
10
被引用文献数
1 1

World trends and problems of amphetamine and methamphetamine abuse, were described. Since the world seizures of the controlled drugs such as opiates, heroin, cocaine, cannabis and other psychotropic substances have rapidly increased in recent years, the author focused on the world-wide spread of amphetamine abuse. The world seizure of stimulant including amphetamines in 1987 has increased by 5-6 fold over in 1982. The trends of amphetamine abuse in many countries were summarized and this report pointed out the past and present problems of amphetamine abuse in U.S.A., Sweden, and Japan. In west coast regions of U.S.A., methamphetamine abuse has surprisingly spread in recent years. The increases of clandestine laboratory have become a big problem in US western states. The trends of amphetamine abuse patterns were introduced. Because of the great risk of acquired immunodeficiency syndrome with intravenous injection drug use, abuse patterns have been changing from injection to inhalation of amphetamines. About a new smokable methamphetamine, so-called "ice", its chemical and pharmacological characters were discussed and its toxicity also described. Additionally, concerning psychotropic drugs chemically and pharmacologically similar to amphetamines, their histories and hallucinogenic activities were described. In paticular, the epidemiologic topics of 3, 4-methylenedioxymethamphetamine (MDMA) called the rivival of LSD was described.
著者
中原 雄二
出版者
公益社団法人 日本薬学会
雑誌
衛生化学 (ISSN:0013273X)
巻号頁・発行日
vol.36, no.2, pp.100-108, 1990
被引用文献数
1

World trends and problems of amphetamine and methamphetamine abuse, were described. Since the world seizures of the controlled drugs such as opiates, heroin, cocaine, cannabis and other psychotropic substances have rapidly increased in recent years, the author focused on the world-wide spread of amphetamine abuse. The world seizure of stimulant including amphetamines in 1987 has increased by 5-6 fold over in 1982. The trends of amphetamine abuse in many countries were summarized and this report pointed out the past and present problems of amphetamine abuse in U.S.A., Sweden, and Japan. In west coast regions of U.S.A., methamphetamine abuse has surprisingly spread in recent years. The increases of clandestine laboratory have become a big problem in US western states. The trends of amphetamine abuse patterns were introduced. Because of the great risk of acquired immunodeficiency syndrome with intravenous injection drug use, abuse patterns have been changing from injection to inhalation of amphetamines. About a new smokable methamphetamine, so-called "ice", its chemical and pharmacological characters were discussed and its toxicity also described. Additionally, concerning psychotropic drugs chemically and pharmacologically similar to amphetamines, their histories and hallucinogenic activities were described. In paticular, the epidemiologic topics of 3, 4-methylenedioxymethamphetamine (MDMA) called the rivival of LSD was described.
著者
中原 雄二
出版者
医学書院
巻号頁・発行日
pp.439-446, 1995-04-15

毛髪薬物分析の歴史に続き,毛髪の組織構造や生態に関して説明し,①毛髪試料の前処理,②毛髪中の薬物の抽出法と分析方法,③薬物使用量と毛髪中薬物濃度の相関,④毛髪中の薬物の移動,⑤毛髪中の薬物分布と薬物使用歴,⑥毛髪中の薬物の安定性,⑦血中薬物濃度の比率と毛髪中濃度,⑧毛髪への薬物取込率,⑨毛髪分析による薬物依存症の診断への試み,⑩覚醒剤ベビー,⑪多剤乱用,の項目で毛髪中薬物分析の基礎から応用まで述べた.〔臨床検査39: 439-446, 1995〕