著者

今西 文男

出版者

公益社団法人 日本ビタミン学会

雑誌

ビタミン (ISSN:0006386X)

巻号頁・発行日

vol.22, no.3, pp.313-322, 1961-03-25 (Released:2017-12-18)

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The lesion of each organ of the rats administrated with 50,000 I.U. of vitamin A-acetate for 7-15 days was examined histologically. After describing the pathological changes of heart, liver, kidneys, brain, peripheral nerve fibers and end-plates in skeletal muscle, bone, endcrine glands etc., the author discussed the effect of synthetic vitamin A on the living bodies comparing with the old examination using liver oil. From the histological finding of thalamo-hypophyseal system, it was pointed out that the hypervitaminosis was regarded as a kind of stressor.