著者

君嶋 葵

出版者

公益社団法人 有機合成化学協会

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.78, no.9, pp.901-903, 2020-09-01 (Released:2020-09-10)

参考文献数

8

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Hippolachnin is a polyketide natural product isolated from the marine sponge Hippospongia lachnein in China 2013, which has shown highly potent antibacterial activities against several pathogenic fungi. It features a highly substituted cyclobutane, six contiguous stereocenters, one of which is quaternary carbon and bears an unusual array of four ethyl groups on its convex face. In this review, total syntheses of hippolachnin by four groups are described.