著者

林 達郎 周 向栄 陳 華岳 原 武史 藤田 広志 横山 龍二郎 桐生 拓司 星 博昭

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.45, no.4, pp.256-266, 2007-12-10 (Released:2008-09-12)

参考文献数

23

被引用文献数

1

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The number of osteoporosis patients is increasing every year in Japan. Multi-detector-row CT is widely used in clinical environment including diagnoses of osteoporosis. However, quantitative evaluation of osteoporosis based on CT images is not defined. This paper investigates the distribution of bone mineral density (BMD) values measured in vertebral trabecular bones from the twelfth thoracic vertebra to the first sacral vertebra in Japanese subjects. Using X-ray CT images of 136 subjects, CT number of vertebral trabecular bones in these regions was measured, and BMD values were estimated from CT number using a bone mineral reference phantom. In addition, the relation of BMD values of each vertebra was investigated, and correlation with age, gender, and fusion at lumbosacral portion was shown. The present study showed that there was no statistical significant difference in BMD values of vertebral trabecular bones from the twelfth thoracic vertebra to the fifth lumbar vertebra. Therefore, among these vertebrae, if the CT number of one vertebra is known, the BMD values of the other vertebrae can be estimated based on the relationships shown by our research.

著者

林 達郎 周 向栄 陳 華岳 原 武史 藤田 広志 横山 龍二郎 兼松 雅之 星 博昭

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.46, no.4, pp.451-457, 2008-08-10 (Released:2009-01-21)

参考文献数

11

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The number of osteoporosis patients is increasing every year in Japan. Bone mineral density (BMD), which is the helpful feature quantity in diagnosing osteoporosis, is generally measured in the central part of the vertebral body. It's possible to measure BMD at each location in X-ray CT images having a high spatial resolution. If bone mineral density of the vertebral body is not homogeneous, grasp of the lower BMD location inside the vertebral body may be helpful to clinical diagnosis. In this paper, using X-ray CT images of 80 subjects (40 male and 40 female subjects), BMDs of trabecular bones from the 12th thoracic vertebra to the 1th sacral vertebra (S1) were measured at each location. The present study showed that anterior and central locations of thoracolumbar and lumbar vertebra, and posterior, inferior, and central locations of S1 had lower BMD values. Therefore, at the thoracolumbar and lumbar vertebra, if the BMDs of anterior or central locations are selectively measured, prediction of fracture risk at vertebral bodies could be improved.