著者

畑山 靖樹 杉山 晴俊 村上 大輔 大浦 弘嵩 嶋 由紀子 白戸 美穂 西野 隆義 新井 誠人 加藤 直也

出版者

一般社団法人 日本肝臓学会

雑誌

肝臓 (ISSN:04514203)

巻号頁・発行日

vol.64, no.12, pp.653-655, 2023-12-01 (Released:2023-12-11)

参考文献数

7

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A Japanese woman in her 30s was diagnosed with hepatitis B surface antigen positivity during pregnancy with her first child. Her liver function was normal; however, high viral load was observed. In accordance with the guidelines, a nucleic acid analog was administered starting at 28 weeks' gestation. The baby was delivered nearly at term, and the nucleic acid analog was discontinued one day prior to the delivery. Liver dysfunction was observed two months after the analog was discontinued, and the patient was restarted on nucleic acid analog treatment. There are many issues to be resolved, including whether nucleic acid analogs should be discontinued immediately following delivery or continued for certain time or whether breastfeeding should continue during nucleic acid analog treatment.