著者

繁田 明義 内山 善康 橋本 紘行 持田 讓治 新福 栄治 大見 博子

出版者

日本肩関節学会

雑誌

肩関節 (ISSN:09104461)

巻号頁・発行日

vol.35, no.3, pp.907-910, 2011 (Released:2011-12-21)

参考文献数

16

被引用文献数

3

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Many studies have reported treatment effects of H2 receptor antagonists (H2RA) on calcific tendinitis (CT) of the shoulder. The purpose of this retrospective study is to compare the clinical outcome between the cimetidine and the famotidine of CT of the shoulder. We studied 72 patients with CT of the shoulder who were closed with H2RA (cimetidine or famotidine) and loxoprofen sodium from 2005. They were treated as follows, 41 with cimetidine and loxoprofen (group C) (14 males, 27 females, average age 54.3 years old) 17 with famotidine and loxoprofen (group F) (10 males, 7 females, average age 58.4 years old) and 14 with loxoprofen(group N) (8 males, 6 females, average age 60.2 years old). Shoulder joint pain was assessed by using visual analogue scale (VAS), and the site and size of calcium deposits were calculated by X-rays (frontal view and scapula Y). In addition, influences of the complicating diseases (diabetes mellitus and hypertension) were evaluated for treatment effects. Groups C and F improved their pain and decreased calcium deposit size more than group N (p<0.05). However, the pain and calcium deposit size was not significantly different between group C and group F. Diabetic patients reduced the effectiveness more than non-diabetic patients in groups C and F. Hypertensive patients reduced the reduction ratio of calcium deposit more than non- hypertensive patients in groups C and F. There were the same clinical results for both cimetidine and famotidine for the CT of the shoulder. Diabetes mellitus and hypertension inhibited the treatment effects of H2RA.