著者

山根 賢治

出版者

THE JAPANESE SOCIETY FOR MULTIPHASE FLOW

雑誌

混相流 (ISSN:09142843)

巻号頁・発行日

vol.29, no.1, pp.35-41, 2015-03-15 (Released:2015-05-02)

参考文献数

8

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To control safe administration of injection product, we should carefully handle foreign matters. Hospital sometimes encountered cases where insoluble matter formed during the preparation of injections. In order to deal with this situation, we discussed the mechanism of formation of the insoluble matter and countermeasures on manufacturing process. Insoluble matter was a critical problem for quality of drug product of injections. In this report, the review for general approach for the foreign matters on injection product was reported.

著者

井上 義之 横山 豊和 山根 賢治 田中 敏嗣 辻 裕

出版者

一般社団法人日本機械学会

雑誌

日本機械学會論文集. C編 (ISSN:03875024)

巻号頁・発行日

vol.63, no.606, pp.356-363, 1997-02-25

被引用文献数

2

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The motion of balls in a tumbling ball mill was simulated numerically using the discrete element method (DEM). Simulations are performed for the two-dimensional and three-dimensional cases. To study the difference between two-dimensional and three-dimensional powder milling analyses, the ball motion was analyzed. It was found that there is no significant difference between the flow patterns for the two-dimensional and three-dimensional cases, but some properties such as the trajectory of the center of the gravity of the balls, the profile of the average velocity vector, the average ball velocity and the fluctuation velocities of the balls show significant differences.