著者

紺野 大地 松本 信圭 鈴木 隆文 池谷 裕二

雑誌

第43回日本神経科学大会

巻号頁・発行日

2020-06-15

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The brain is intrinsically active even in the absence of external stimuli. Although many researches have studied spontaneous brain activity, few studies have examined the differences in oscillatory frequency, it remained whether the patterns of spontaneous brain activity are similar between different oscillatory frequencies. To address this question, we recorded electrocorticograms (ECoGs) from the visual cortex of free moving rats. ECoG is a well-balanced neural signal, which is stably mapped brain surface local field potentials over a wide cortical region with high signal fidelity and minimal invasiveness to the brain tissue. The ECoG probe used in this study had 32 electrodes on a mesh structure to stably contact them onto the brain surface. We found that the across-electrode propagation pattens of spontaneous brain activity differed across oscillatory frequency bands. For examples, the spatial propagations of delta- and alpha-band activity tended to exhibit an inverse correlation. On the other hand, the propagations of beta- and gamma-band activity were similar. In addition, the spontaneous activity patterns were classified into several clusters using uniform manifold approximation and projection (UMAP) and affinity propagation algorithms. These results reveal a complex relationship between spontaneous brain activity and oscillatory frequencies.