著者

滝沢 由政 胡桃坂 仁志

出版者

日本結晶学会

雑誌

日本結晶学会誌 (ISSN:03694585)

巻号頁・発行日

vol.64, no.1, pp.65-68, 2022-02-28 (Released:2022-03-04)

参考文献数

9

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Chromatin is a highly organized complex of genomic DNA and proteins in eukaryotic cells. Fundamental unit of chromatin is nucleosome composed of histone octamer and approximately 150 base pairs of DNA. The higher-order conformation of chromatin is involved in important genomic events such as replication, transcription, recombination, and repair. Recently various structures chromatin have been determined by cryo-electron microscopy (cryo-EM). Based on our cryo-EM studies, in this article, we introduce current structures of chromatin determined by cryo-EM.