著者

太田 伸 長井 克浩 全田 浩 牧野 公博

出版者

日本医療薬学会

雑誌

病院薬学 (ISSN:03899098)

巻号頁・発行日

vol.18, no.3, pp.196-203, 1992-06-20

被引用文献数

1

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The present study was performed to estimate the efficacy of antirust and disinfection of new compounds (P1-E, P2-E, P3-E, P4-E, P2-PG1, P3-PG1, P4-PG1) as shown in Table 1 in comparison with commercial disinfectants [chlorhexidine digluconate (CHX), benzalkonium chloride (BAC) and alkyldiaminoethylglycine hydrochloride (ADE)]. Antirusting effects of new compounds were evaluated by counting the numbers of rusts on the ten pins. The antirusting effects of new compounds were higher than those of CHX, BAC and ADE. Rusts were produced after 6hr in the case of BAC. Effects of new compounds and disinfectants against clinical isolated pathogenic microorganisms were determined by minimum inhibitory concentration (MIC). Antimicrobial activities of P1-E, P2-E, P3-E and P4-E were equivalent to that of BAC or ADE, while effects of disinfection of P2-PG1, P3-PG1 and P4-PG1 were higher than that of BAC or ADE. Compatibilities of new compounds with various disinfectants or sodium lauryl sulfate (SLS) were tested in each combination, P1-E, P2-E, P3-E, P4-E and P4-PG1 had good compatibilities to the various disinfectants and the SLS in the case of each combination. These results indicated that the new compounds were very useful as antirusty disinfectants.