- 著者
- 田中 博道 松田 彰 飯島 秀治 早川 弘之 宮坂 貞
- 出版者
- The Pharmaceutical Society of Japan
- 雑誌
- Chemical and Pharmaceutical Bulletin (ISSN:00092363)
- 巻号頁・発行日
- vol.31, no.6, pp.2164-2167, 1983-06-25 (Released:2008-03-31)
- 参考文献数
- 9
- 被引用文献数
- 25 40
A new class of 5, 6-disubstituted uridines, in which the C-6 position was occupied by phenylthio group or iodine, were synthesized via lithiation of the corresponding 5-substituted 2', 3'-O-isopropylidene-5'-O-methoxymethyluridines and subsequent electrophilic reactions. These newly-synthesized uridine derivatives exhibited antileukemic activities against mouse leukemia L5178Y cells in culture.