- 著者
-
Tetsuya SHIMODA
Mika TANABE
Yuuki SHOJI
Takuya KANDA
Kouhei KISHIDA
Ai KISHIDA
Atsushi HASHIMOTO
Mako OTSUKA
Akina MIYAMOTO
Tomoko KAWAKITA
Wataru OSHITA
Reijiro HIRAO
Akihisa SUWA
- 出版者
- JAPANESE SOCIETY OF VETERINARY SCIENCE
- 雑誌
- Journal of Veterinary Medical Science (ISSN:09167250)
- 巻号頁・発行日
- vol.84, no.2, pp.251-256, 2022 (Released:2022-02-23)
- 参考文献数
- 22
- 被引用文献数
-
2
A cat was presented with depression and anorexia. The complete blood cell count (CBC) revealed non-regenerative anemia (PCV, 8.5%), marked thrombocytopenia (2,400/µl), and leukocytosis (32,090/µl). In the peripheral blood, proliferation of blast cells (85%; 27,276/µl) and basophils (7.7%; 2,460/µl) was observed. Bone marrow aspirate showed hyperplasia with 8.8% blasts and 90.2% basophils of all nucleated cells. The blast cells were negative for myeloperoxidase staining and positive for alpha-naphthol butyrate esterase staining, indicating the agranular blasts are monoblasts. Thus, acute monoblastic leukemia (M5a) with chronic basophilic leukemia was diagnosed. Basophils accounted for more than 40% of the bone marrow, and we diagnosed secondary basophilic leukemia. Secondary basophilic leukemia should be included in the differential list when abnormal basophil increases are observed in feline bone marrow.