著者

Tadafumi Sugimoto Kaoru Dohi Katsuya Onishi Tomomi Yamada Masahide Horiguchi Takeshi Takamura Akihiro Kawamura Tetsuya Seko Mashio Nakamura Atsunobu Kasai Masaaki Ito

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.78, no.11, pp.2704-2710, 2014-10-24 (Released:2014-10-24)

参考文献数

42

被引用文献数

3 6

---

Background:Secondary hyperparathyroidism develops as a compensatory response to chronic heart failure (HF) and renal failure. The role of parathyroid hormone (PTH) level in acute decompensated HF remains unclear. The aim of this study was therefore to investigate the relationships among mortality, renal function, and serum PTH level in acute decompensated HF patients.Methods and Results:A total of 266 consecutive patients admitted for acute decompensated HF without acute coronary syndrome (78±12 years; 48% male) were enrolled. Demographic, clinical, and laboratory characteristics were obtained on admission.During 1-year follow-up, 65 patients (24%) died. Serum PTH level on admission was within the normal range (10–65 pg/ml) in 108 patients (41%), of whom 39 (15%) had low-normal PTH (10–40 pg/ml). On Kaplan-Meier analysis all-cause mortality was significantly higher in patients with low-normal PTH than in those with high-normal (40–65 pg/ml) or high (>65 pg/ml) PTH (log-rank test). On univariate and multivariate Cox regression analysis, low-normal PTH was significantly associated with increased all-cause mortality (unadjusted HR, 2.88; 95% CI: 1.69–4.91; P<0.001; adjusted HR, 3.84; 95% CI: 1.54–9.57; P=0.004).Conclusions:In patients with acute decompensated HF resulting in hospitalization, low-normal PTH on admission is associated with increased all-cause mortality, regardless of renal function. (Circ J 2014; 78: 2704–2710)

著者

"杉本 篤信" "スギモト アツノブ" Atsunobu" "Sugimoto

雑誌

経営情報研究 : 摂南大学経営情報学部論集

巻号頁・発行日

vol.16, no.2, pp.11-28, 2009-02

---

"ケインズ経済学において,独立支出の増加がGDPに乗数倍だけの増加をもたらすという「乗数理論」は,財政政策の効果に大きな期待をさせる理論的根拠になっている.しかし,日本の90年代の長期不況期に財政政策の効果は小さくなったと認識され,ケインズの経済学への信頼が薄れてきた.それに対して,伊東光晴氏はその著書において,90年代の資産デフレ不況下において,政府支出の増加は,在庫投資や投資の減少により,財政政策の効果が弱められたのであったと主張する.本稿では,この伊東氏の見解を,データを通して計量的手法で考察した.結果は,伊東氏の主張は裏付けられず,90年代の政府支出と在庫投資や投資との相関関係はなかったと推察される."