- 著者
- Shiho Toyama Ayuko Takatani Tomohiro Koga Mizuna Eguchi Momoko Okamoto Sosuke Tsuji Yushiro Endo Toshimasa Shimizu Remi Sumiyoshi Takashi Igawa Shin-ya Kawashiri Naoki Iwamoto Kunihiro Ichinose Mami Tamai Hideki Nakamura Tomoki Origuchi Masako Furuyama Maiko Tabuchi Shinichiro Kobayashi Kengo Kanetaka Mikiko Hashisako Kuniko Abe Daisuke Niino Shinya Sato Yasushi Miyazaki Atsushi Kawakami
- 出版者
- The Japanese Society of Internal Medicine
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- pp.2782-19, (Released:2019-07-22)
- 参考文献数
- 20
- 被引用文献数
- 1
A 71-year-old woman being treated with methotrexate (MTX) and tacrolimus (TAC) for rheumatoid arthritis (RA) was admitted to our hospital and underwent surgery for gastric perforation and peritonitis. An endoscopic examination six days post-surgery showed an extensive ulcer in the stomach, and a biopsy revealed diffused large B-cell lymphoma. We diagnosed her with immunodeficiency-associated lymphoproliferative disorder (LPD) and discontinued the MTX and TAC. She underwent gastrectomy due to stenosis approximately two months after the first operation, but the histopathological findings of lymphoma had disappeared. LPD should be considered as a potential cause of gastric perforation during RA treatment.
- 著者
- Shota Kurushima Yoshiro Horai Ayuko Takatani Ayako Nishino Shin-ya Kawashiri Kunihiro Ichinose Hideki Nakamura Atsushi Kawakami
- 出版者
- 一般社団法人 日本内科学会
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- pp.9195-17, (Released:2017-10-11)
- 参考文献数
- 8
- 被引用文献数
- 3
We herein report a woman in her 50s with systemic lupus erythematosus (SLE) who developed swelling and pain in her fingers; the symptoms were more prominent in winter. Magnetic resonance imaging (MRI) revealed bone edema in the phalanges of both hands, which was compatible with phalangeal microgeodic syndrome (PMS). This is the first reported case of PMS in a patient with SLE and suggests that performing MRI should be considered for patients with SLE in order to assess the nature of finger symptoms and signs more precisely.