著者

Tadahisa Numakura Koji Murakami Tsutomu Tamada Chiaki Yamaguchi Chihiro Inoue Shinya Ohkouchi Naoki Tode Hirohito Sano Hiroyuki Aizawa Kei Sato Ayumi Mitsune Hajime Kurosawa Toru Nakazawa Hisatoshi Sugiura

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

pp.0104-22, (Released:2022-08-10)

参考文献数

23

被引用文献数

15

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BNT162b2 (Pfizer/BioNTech) is a coronavirus disease 2019 (COVID-19) vaccine containing nucleoside-modified messenger RNA encoding the severe acute respiratory syndrome coronavirus 2 spike glycoprotein. Recently, ocular complications of mRNA vaccines have been reported increasingly frequently. However, immunological adverse events due to mRNA vaccines in real-world settings are not fully known. We herein report the novel development of sarcoidosis manifested as uveitis, bilateral hilar lymphadenopathy, angiotensin-converting enzyme elevation, and epithelioid and giant cell granuloma formation in the lung soon after the first BNT162b2 injection and review the current literature, including three reported cases of sarcoid-like reaction following COVID-19 vaccination.

著者

Tadahisa Numakura Koji Murakami Tsutomu Tamada Chiaki Yamaguchi Chihiro Inoue Shinya Ohkouchi Naoki Tode Hirohito Sano Hiroyuki Aizawa Kei Sato Ayumi Mitsune Hajime Kurosawa Toru Nakazawa Hisatoshi Sugiura

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.61, no.20, pp.3101-3106, 2022-10-15 (Released:2022-10-15)

参考文献数

23

被引用文献数

15

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BNT162b2 (Pfizer/BioNTech) is a coronavirus disease 2019 (COVID-19) vaccine containing nucleoside-modified messenger RNA encoding the severe acute respiratory syndrome coronavirus 2 spike glycoprotein. Recently, ocular complications of mRNA vaccines have been reported increasingly frequently. However, immunological adverse events due to mRNA vaccines in real-world settings are not fully known. We herein report the novel development of sarcoidosis manifested as uveitis, bilateral hilar lymphadenopathy, angiotensin-converting enzyme elevation, and epithelioid and giant cell granuloma formation in the lung soon after the first BNT162b2 injection and review the current literature, including three reported cases of sarcoid-like reaction following COVID-19 vaccination.

著者

Chihiro Inoue Ryo Nishiyama Yasuhiro Fujisaki Toshiaki Kitagawa

出版者

Japan Explosives Society

雑誌

Science and Technology of Energetic Materials (ISSN:13479466)

巻号頁・発行日

vol.81, no.5, pp.121-127, 2020 (Released:2020-11-09)

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A traditional Japanese sparkler, senko-hanabi, is consists of paper string wrapping 0.1 g of black powder. The sparkler requires heat production by combustion of contained charcoal with ambient oxygen, showing off beautiful sparks luminous by heat radiation. In the present study, the appearance of the sparks is investigated under various ambient conditions, in which the total pressure is from vacuum to 5.0 bar and the oxygen concentration rate is set up to 40 %. The sparkler is ignited by Joule heating inside a closed vessel. Profound effects are confirmed by the ambient conditions on the sparks. As the total pressure rises, sparks spread actively, because the boundary layer surrounding the fireball, created at the bottom end of the paper string, becomes thinner, and the amount of oxygen supply increases. The oxygen concentration rate directly contributes to the amount of oxygen supply. The criterion given by molar flux of oxygen supply to the fireball is identified as 10-1 mol · s-1 · m-2, rate-controlled by molecular diffusion through the boundary layer, for embodying fragile beauty over the centuries.