2 0 0 0 OA Identification of Cell Surface Antigen Expression in Canine Hepatocellular Carcinoma Cell Lines
- 著者
- Ayumi FUJIMOTO Sakurako NEO Chinatsu ISHIZUKA Takashi KATO Kazuhito SEGAWA Shinpei KAWARAI Kikumi OGIHARA Masaharu HISASUE Ryo TSUCHIYA
- 出版者
- 公益社団法人 日本獣医学会
- 雑誌
- Journal of Veterinary Medical Science (ISSN:09167250)
- 巻号頁・発行日
- pp.12-0549, (Released:2013-02-13)
- 被引用文献数
- 1 7
The characteristics of surface antigens in canine hepatocellular carcinoma (cHCC) have not been clarified. The objective of this study was to investigate surface antigens, which are considered as stem/progenitor or cancer cell markers, in cHCC cell lines. Expression of various antigens including CD29, CD34, CD44, CD90, CD133 and Dlk-1 was assessed in four cHCC cell lines by flow cytometry. CD44, CD133 and Dlk-1 expression was detectable in all cell lines, and three cell lines expressed CD29. These results indicate that CD29, CD44, CD133 and Dlk-1 have potential as suitable markers in cHCC identification, suggesting that these findings will contribute to the establishment of an early diagnostic tool for the identification of hepatocellular maturation processes.
1 0 0 0 OA Identification of Cell Surface Antigen Expression in Canine Hepatocellular Carcinoma Cell Lines
- 著者
- Ayumi FUJIMOTO Sakurako NEO Chinatsu ISHIZUKA Takashi KATO Kazuhito SEGAWA Shinpei KAWARAI Kikumi OGIHARA Masaharu HISASUE Ryo TSUCHIYA
- 出版者
- 公益社団法人 日本獣医学会
- 雑誌
- Journal of Veterinary Medical Science (ISSN:09167250)
- 巻号頁・発行日
- vol.75, no.6, pp.831-835, 2013 (Released:2013-07-01)
- 参考文献数
- 22
- 被引用文献数
- 1 7
The characteristics of surface antigens in canine hepatocellular carcinoma (cHCC) have not been clarified. The objective of this study was to investigate surface antigens, which are considered as stem/progenitor or cancer cell markers, in cHCC cell lines. Expression of various antigens including CD29, CD34, CD44, CD90, CD133 and Dlk-1 was assessed in four cHCC cell lines by flow cytometry. CD44, CD133 and Dlk-1 expression was detectable in all cell lines, and three cell lines expressed CD29. These results indicate that CD29, CD44, CD133 and Dlk-1 have potential as suitable markers in cHCC identification, suggesting that these findings will contribute to the establishment of an early diagnostic tool for the identification of hepatocellular maturation processes.