- 著者
- Gerhard N. SCHRAUZER Tammy MOLENAAR Sherri MEAD Klaus KUEHN Hiroshi YAMAMOTO Eiji ARAKI
- 出版者
- The Japanese Cancer Association
- 雑誌
- Japanese Journal of Cancer Research GANN (ISSN:09105050)
- 巻号頁・発行日
- vol.76, no.5, pp.374-377, 1985 (Released:2008-03-17)
- 参考文献数
- 15
Selenium concentrations in whole blood of Japanese and American women with and without breast cancer and benign fibrocystic breast disease were determined. The observed blood Se levels of healthy Japanese women (0.286±0.021μg/ml) were similar to previously reported values for healthy Japanese adults. The Japanese patients with benign breast disease and with breast cancer exhibited blood selenium concentrations of 0.200±0.045 and 0.195±0.057μg/ml, respectively. The mean blood Se concentration of Japanese breast cancer patients with recurrence was 0.188±0.061μg/ml. The mean blood Se concentrations of healthy American women from San Diego, Calif., were 0.191±0.023μg/ml; of women with benign fibrocystic disease, 0.142±0.010μg/ml; and of breast cancer patients, 0.167±0.032μg/ml. The higher blood Se concentrations of Japanese healthy subjects as compared to healthy Americans can be attributed to differences in the dietary Se intakes; low blood Se concentration may be indicative of increased breast cancer risk.
- 著者
- Yuko NAGATA Mutsuko YOSHIDA Eiji ARAKI Toshiharu GOMYO
- 出版者
- 社団法人 日本食品科学工学会
- 雑誌
- Food Science and Technology Research (ISSN:13446606)
- 巻号頁・発行日
- vol.18, no.6, pp.885-891, 2012 (Released:2013-01-11)
- 参考文献数
- 35
The effects of single administration of Lactobacillus plantarum No. 14 (LP14) on human body temperature and factors related to sympathetic nerves were measured in a randomized, double-blind, cross-over study. LP14 significantly increased chest temperature (P < 0.05). The maximum difference in temperature between LP14 and placebo was 0.24 ± 0.24℃. Systolic blood pressure increased significantly, and arousal scores tended to increase in the LP14 group. The results of the Uchida-Kraepelin test indicated that LP14 elevated task performance. Our results demonstrated that LP14 induced thermogenesis in humans. We also examined the activity of the sympathetic nerves (SNA) innervating brown adipose tissue (BAT) in rats. The activity of BAT-SNA was significantly enhanced in the LP14 group. As LP14 changed factors associated with sympathetic nerves in humans and elevated sympathetic nerve activity in rats, sympathetic nerve activation appears to participate in thermogenesis elicited by LP14.