著者
Haruna Fujisawa Yurika Mitsui Kensuke Narukawa Yukari Shirasugi Shogo Komaki Akihito Hao Hideyuki Matsumoto Tsuyoshi Takahashi
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
pp.0855-22, (Released:2022-12-07)
参考文献数
16
被引用文献数
1

A 21-year-old woman was diagnosed with acute lymphoblastic leukemia. After the administration of intrathecal methotrexate (MTX), the patient experienced dysarthria and paralysis for one hour. Magnetic resonance imaging (MRI) performed one hour from the onset and just before symptoms disappeared revealed no abnormalities. The next day, the symptoms appeared again, and diffusion-weighed MRI revealed a high-intensity area in the left frontal lobe. The patient was diagnosed with MTX-induced encephalopathy. This case suggested that MRI performed as soon as symptoms appear might show normal findings in MTX-induced encephalopathy.
著者
Masakazu Hirotsu Shinsuke Taruno Takashi Yoshimura Keiji Ueno Masafumi Unno Hideyuki Matsumoto
出版者
(社)日本化学会
雑誌
Chemistry Letters (ISSN:03667022)
巻号頁・発行日
vol.34, no.11, pp.1542-1543, 2005 (Released:2005-10-15)
参考文献数
27
被引用文献数
28

The first titanium(IV) complexes with cyclic tetrasiloxide ligands, [Ti(L1H)(OSiMe3)]2(H2O) (1) and (CpTiCl)4(L2)2 (2), were synthesized using the all-cis isomer of cyclotetrasiloxanetetraols R4(SiO)4(OH)4 (L1H4: R = Ph, L2H4: R = iPr) as ligand precursors. X-ray analysis revealed that 1 is a dinuclear complex with bridging siloxy and aqua ligands while 2 has a tetranuclear cage structure capped by two L2 ligands.