- 著者
- Keisuke Kinoshita Miyuki Yamaguchi Hirohisa Sasou Hideyuki Konishi Kei Manabe
- 出版者
- The Pharmaceutical Society of Japan
- 雑誌
- Chemical and Pharmaceutical Bulletin (ISSN:00092363)
- 巻号頁・発行日
- vol.71, no.2, pp.175-182, 2023-02-01 (Released:2023-02-01)
- 参考文献数
- 51
- 被引用文献数
- 1
Palladium-catalyzed, hydroxy-group-directed C–H arylation of [1,1′-biphenyl]-2-ols with chloroarenes was performed. The reaction showed a broad substrate scope and was successfully applied to pharmaceuticals containing a chloro group. Using 2-heteroarylphenols instead of [1,1′-biphenyl]-2-ols also yielded the desired products. The arylated product was further transformed into a triphenylene derivative.