- 著者
- Hiroshi Koga Atsushi Yamagishi Atsushi Takayanagi Kohji Maeda Takashi Matsukubo
- 出版者
- Tokyo Dental College, Japan
- 雑誌
- The Bulletin of Tokyo Dental College (ISSN:00408891)
- 巻号頁・発行日
- vol.48, no.3, pp.119-128, 2007 (Released:2007-12-05)
- 参考文献数
- 16
- 被引用文献数
- 7 9
Fluoride dentifrice has been accepted widely for use in caries prevention and its effectiveness has been confirmed. In order to enable the use of fluoride dentifrice effectively in daily brushing, the present study was performed to examine the relationship between fluoride uptake and the amount of fluoride dentifrice used and brushing time for adults. We examined the relationship between fluoride uptake into the surface layer (4-6 μm)of enamel and the active fluoride concentration in vitro and the relationship between the amount of fluoride dentifrice (1,000ppmF) used and the fluoride concentration in oral fluid in vivo. It became clear that fluoride uptake into the enamel was increased at the concentrations of 300ppmF or more. Fluoride uptake at 300ppmF was increased for 2min and became saturated thereafter. The results of the relationship between the fluoride concentration in the oral fluid and the amount of fluoride dentifrice used indicated that the amount of dentifrice that could maintain the mean fluoride concentration at 300ppm or more for 2min was 1.0g or more. From these results, the recommended amount of fluoride dentifrice (1,000ppmF) is 1.0g or more for adults.
- 著者
- Makoto Nakao Hideki Muramatsu Tetsushi Takahashi Shunsuke Niwa Yusuke Kagawa Ryota Kurokawa Kazuki Sone Yuki Uozumi Misako Ohkusu Katsuhiko Kamei Hiroshi Koga
- 出版者
- 一般社団法人 日本内科学会
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.55, no.20, pp.3021-3024, 2016-10-15 (Released:2016-10-15)
- 参考文献数
- 17
- 被引用文献数
- 10
A 39-year-old man presented to our hospital with a four-week history of headache and a two-week history of low-grade fever. Chest X-rays showed a tumor of approximately 50 mm in size in the right lower field. A histopathological examination of a transbronchial lung biopsy specimen from the right S9/10 revealed numerous fungal elements that appeared as encapsulated yeast with clear halos. Gadolinium-enhanced brain magnetic resonance images showed multiple cerebral nodules. Cryptococcus gattii (Genotype VGIIa) was isolated from the bronchial lavage and cerebrospinal fluid specimens. The patient was an immunocompetent Japanese man who had not recently traveled to a C. gattii-endemic area.