- 著者
- Hirotaka YANAGAWA Hitoshi HATAI Takahiro TAODA Hassadin BOONSRIROJ Kazunori KIMITSUKI Chun-Ho PARK Toshifumi OYAMADA
- 出版者
- 公益社団法人 日本獣医学会
- 雑誌
- Journal of Veterinary Medical Science (ISSN:09167250)
- 巻号頁・発行日
- pp.14-0097, (Released:2014-03-26)
- 被引用文献数
- 1 9
An 11-year-old mixed breed dog was presented with signs of anorexia. Radiographic and ultrasound examination revealed a large mass in the heart, between the right atrium and the right ventricle. Upon gross inspection, a multilobulated tumor arising from the right atrial wall and occupying the right atrium was identified. Microscopical analysis demonstrated that this tumor consisted of neoplastic cells with granular cytoplasm, which were separated into nests by fine fibrovascular stroma, and was negative for Grimelius’s method. Immunohistochemical examinations revealed that the neoplastic cells expressed chromogranin A, synaptophysin and neuron specific enolase. Electron microscopy revealed that the cytoplasm of the neoplastic cells held secretory granules. Based on these pathological findings, the tumor was diagnosed as a paraganglioma. This report is a rare case of primary paraganglioma deriving from the right atrium and provides a detailed characterization of its morphological features.