著者

Masahito Hitosugi Masashi Ikeda Xia Zhu Hisayoshi Kato Kazunobu Omura Toshiaki Nagai Shogo Tokudome

出版者

Japanese Society of Biorheology

雑誌

日本バイオレオロジー学会誌 (ISSN:09134778)

巻号頁・発行日

vol.21, no.1, pp.35-40, 2007-03-25 (Released:2012-09-24)

参考文献数

12

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We compared the anticoagulant and fibrinolytic effects of the major functional food products generated by Bacillus subtilis natto. We analyzed NSK-SDR and NKCPR powders that consist mainly of nattokinase and bacillopeptidase F, respectively. The specific activity of the plasmin-like activity of NKCPR H was about 2.5-fold higher than that of NSK-SDR. Although both NSK-SDR and NKCPR reduced fibrin monomer levels in human blood, the anticoagulant effect of NKCPR was over 100-fold higher than that of NSK-SDR. Dietary supplements with anticoagulant and fibrinolytic effects might play an important role in preventing thrombotic diseases.