- 著者
- Ogbomida Emmanuel Temiotan Nakayama Shouta M. M. Bortey-Sam Nesta Oroszlany Balazs Tongo Isioma Enuneku Alex Ajeh Ozekeke Ogbeide Ainerua Martins Oshioriamhe Fasipe Iriagbonse Priscillia Ezemonye Lawrence Ikechukwu Mizukawa Hazuki Ikenaka Yoshinori Ishizuka Mayumi Ogbomida Emmanuel Temiotan Nakayama Shouta M. M. Bortey-Sam Nesta Oroszlany Balazs Tongo Isioma Enuneku Alex Ajeh Ozekeke Ogbeide Ainerua Martins Oshioriamhe Fasipe Iriagbonse Priscillia Ezemonye Lawrence Ikechukwu Mizukawa Hazuki Ikenaka Yoshinori Ishizuka Mayumi Ogbomida Emmanuel Temiotan Nakayama Shouta M. M. Bortey-Sam Nesta Oroszlany Balazs Tongo Isioma Enuneku Alex Ajeh Ozekeke Ogbeide Ainerua Martins Oshioriamhe Fasipe Iriagbonse Priscillia Ezemonye Lawrence Ikechukwu Mizukawa Hazuki Ikenaka Yoshinori Ishizuka Mayumi
- 出版者
- Elsevier
- 雑誌
- Ecotoxicology and environmental safety (ISSN:01476513)
- 巻号頁・発行日
- vol.151, pp.92-102, 2018-04-30
- 被引用文献数
- 44
The use of free range animals for monitoring environmental health offers opportunities to detect exposure and assess the toxicological effects of pollutants in terrestrial ecosystems. Potential human health risk of dietary intake of metals and metalloid via consumption of offal and muscle of free range chicken, cattle and goats by the urban population in Benin City was evaluated. Muscle, gizzard, liver and kidney samples were analyzed for Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Cd, and Pb concentrations using inductively coupled plasma mass spectrometer (ICP-MS) while Hg was determined using Hg analyzer. Mean concentrations of metals (mg/kg ww) varied significantly depending upon the tissues and animal species. Human health risk estimations for children and adults showed estimated daily intake (EDI) values of tissues below oral reference dose (RfD) threshold for non essential metals Cd, As, Pb and Hg thus strongly indicating no possible health risk via consumption of animal based food. Calculated Hazard quotient (THQ) was less than 1 (< 1) for all the metals analyzed for both adult and children. However, Cd and As had the highest value of THQ suggestive of possible health risk associated with continuous consumption of Cd and As contaminated animal based foods. Hazard Index (HI) for additive effect of metals was higher in chicken liver and gizzard for children and chicken liver for adults. Thus, HI indicated that chicken liver and gizzard may contribute significantly to adult and children dietary exposure to heavy metals. Principal component analysis (PCA) showed a clear species difference in metal accumulation between chickens and the ruminants. This study provides baseline data for future studies and also valuable evidence of anthropogenic impacts necessary to initiate national and international policies for control of heavy metal and metalloid content in food items.
- 著者
- Ikenaka Yoshinori Miyabara Yuichi Ichise Takahiro Nakayama Shouta Nimako Collins Ishizuka Mayumi Tohyama Chiharu
- 出版者
- John Wiley & Sons
- 雑誌
- Environmental toxicology and chemistry (ISSN:07307268)
- 巻号頁・発行日
- vol.38, no.1, pp.71-79, 2019-01
- 被引用文献数
- 57
Neonicotinoid insecticides that have been on the market since 1992 have been used globally including in Japan. Because they are sprayed over forests and agricultural areas, inadvertent toxicity in nontarget insects (especially honey bees) and humans is a matter of public concern. However, information on exposure levels and potential health impacts of neonicotinoids in children living around sprayed areas is scarce. Thus, we determined neonicotinoid exposure levels in children living in communities where thiacloprid was used to control pine wilt disease. A total of 46 children (23 males and 23 females) were recruited for the present study, and informed written consent was obtained from their guardians. Urine specimens were collected before, during, and after insecticide spraying events; and atmospheric particulate matter was also collected. Concentrations of thiacloprid and 6 other neonicotinoid compounds were determined in urine samples and in atmospheric particulate matter specimens using liquid chromatography-electrospray ionization-tandem mass spectrometry. In urine specimens, thiacloprid concentrations were <0.13 mu g/L and were detectable in approximately 30% of all samples. Concentrations of the other neonicotinoids, N-dm-acetamiprid, thiamethoxam, dinotefuran, and clothianidin, were 18.7, 1.92, 72.3, and 6.02 mu g/L, respectively. Estimated daily intakes of these neonicotinoids were then calculated from urinary levels; although the estimated daily intakes of the neonicotinoids were lower than current acceptable daily intake values, the children were found to be exposed to multiple neonicotinoids on a daily basis. Environ Toxicol Chem 2019;38:71-79. (c) 2018 SETAC