- 著者
- Liang CONG Jing-Ting MA Zhen-Jing JIN Li-Wei DUAN Wei-Ping SU Jing ZHENG Ling-Juan ZHANG Jia XU Dong-Fu LI
- 出版者
- Center for Academic Publications Japan
- 雑誌
- Journal of Nutritional Science and Vitaminology (ISSN:03014800)
- 巻号頁・発行日
- vol.61, no.4, pp.326-331, 2015 (Released:2015-10-06)
- 参考文献数
- 12
- 被引用文献数
- 2
We investigated the efficacy and safety of a new type of dietary fiber (high specific volume polysaccharide) for use in treating constipation of different etiologies. Functional constipation patients and irritable bowel syndrome-constipation (IBS-C) patients were administrated high specific volume polysaccharide (HSVP) three times daily for a period of 2 wk to relieve their symptoms. Scores on a stool form scale, and patient reports of straining during a bowel movement, having sensations of an incomplete bowel movement or a blocked anorectum, and abnormal defecation intervals were recorded, graded, and scored by a functional constipation sample group. Similarly, a cohort of IBS-C patients reported their occurrence of abdominal discomfort or pain, abnormal stool formation, defecation frequency, and straining during a bowel movement. Additionally, both groups reported any adverse reactions associated with taking HSVP. All patients in both groups returned for follow-up visits, and no adverse reactions to treatment with HSVP were reported. In the functional constipation group, HSVP was effective for treating symptoms of constipation in 81.46% and 93.17% of patients after 7 and 14 d of dosing, respectively (both p<0.05). In the IBS-C group, symptoms of constipation were relieved in 71.67% and 88.34% of patients after 7 and 14 d of dosing, respectively (both p<0.05). High specific volume polysaccharide was shown be effective for treatment of functional constipation and IBS-C, without causing significant adverse events.
- 著者
- Li DING Jing JIN Jianjun ZHOU
- 出版者
- The Institute of Electronics, Information and Communication Engineers
- 雑誌
- IEICE TRANSACTIONS on Fundamentals of Electronics, Communications and Computer Sciences (ISSN:09168508)
- 巻号頁・発行日
- vol.E105-A, no.11, pp.1443-1449, 2022-11-01
This brief presents A 16/32Gb/s dual-mode transmitter including a linearity calibration loop to maintain amplitude linearity of the SST driver. Linearity detection and corresponding master-slave power supply circuits are designed to implement the proposed architecture. The proposed transmitter is manufactured in a 22nm FD-SOI process. The linearity calibration loop reduces the peak INL errors of the transmitter by 50%, and the RLM rises from 92.4% to 98.5% when the transmitter is in PAM4 mode. The chip area of the transmitter is 0.067mm2, while the proposed linearity enhanced part is 0.05×0.02mm2 and the total power consumption is 64.6mW with a 1.1V power supply. The linearity calibration loop can be detached from the circuit without consuming extra power.