- 著者
- Jun Matsuyama Kunihiro Tsuji Hisashi Doyama Fae Kim Yasuhito Takeda Yosuke Kito Renma Ito Hiroyoshi Nakanishi Tomoyuki Hayashi Yohei Waseda Shigetsugu Tsuji Kenichi Takemura Shinya Yamada Toshihide Okada Honin Kanaya
- 出版者
- 一般社団法人 日本内科学会
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.51, no.16, pp.2231-2234, 2012 (Released:2012-08-15)
- 参考文献数
- 18
- 被引用文献数
- 8 17
Severe hypomagnesemia is a serious clinical condition. Proton pump inhibitor (PPI) induced hypomagnesemia has been recognized since 2006. In March 2011 the U.S. Food and Drug Administration advised that long-term use of PPI can induce hypomagnesemia. We report the first Japanese case of hypomagnesemia associated with chronic use of PPIs in a 64-year-old man hospitalized for nausea, bilateral ankle arthritis, and tremor of the extremities who had convulsions 3 days after admission. Blood analysis showed severe hypomagnesemia. He had been taking rabeprazole (10 mg/day) for 5 years. After stopping rabeprazole and correcting the electrolytes imbalances, his symptoms improved without recurrence.