著者
Hajime Maeda Hirofumi Mukae Kazuhiko Mizuno
出版者
(社)日本化学会
雑誌
Chemistry Letters (ISSN:03667022)
巻号頁・発行日
vol.34, no.1, pp.66-67, 2005 (Released:2004-12-11)
参考文献数
26
被引用文献数
76 64

The intramolecular photocycloaddition of a 1-cyanonaphthalene derivative in microreactors made of poly(dimethylsiloxane) (PDMS) was examined. By using the microreactors and flow system, both the efficiency and regioselectivity increased compared with those under batch conditions.
著者
Hiroshi Ikeda Kazuki Matsuo Yasunori Matsui Masaya Matsuoka Kazuhiko Mizuno
出版者
The Chemical Society of Japan
雑誌
Bulletin of the Chemical Society of Japan (ISSN:00092673)
巻号頁・発行日
pp.1104260289, (Released:2011-05-07)
参考文献数
67
被引用文献数
3

The mechanism of the Cope rearrangement of 1,5-hexadienes remains controversial. Two pathways for the rearrangement of 2,5-diphenyl-1,5-hexadiene have been debated over the past several decades. The first is a concerted route that takes place via a pericyclic transition state and the other is a stepwise process via a biradical intermediate or biradicaloid transition structure. In this study, we explored a new intramolecular trapping approach to examine the possible existence of the putative biradical that might intervene in the stepwise Cope rearrangement. For this purpose, a study was carried out in which a 1,5-hexadiene, bearing two lophyl radicals at C2 and C5 positions, moieties capable of trapping a putative biradical intermediate intramolecularly, was designed, generated, and characterized both experimentally and with density functional theory.