著者

Kei Hayashi Ichiro Kawachi Tetsuya Ohira Katsunori Kondo Kokoro Shirai Naoki Kondo

出版者

日本疫学会

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.26, no.10, pp.546-552, 2016-10-05 (Released:2016-10-05)

参考文献数

32

被引用文献数

41

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Background: We sought to evaluate the associations between frequency of daily laughter with heart disease and stroke among community-dwelling older Japanese women and men.Methods: We analyzed cross-sectional data in 20 934 individuals (10 206 men and 10 728 women) aged 65 years or older, who participated in the Japan Gerontological Evaluation Study in 2013. In the mail-in survey, participants provided information on daily frequency of laughter, as well as body mass index, demographic and lifestyle factors, and diagnoses of cardiovascular disease, hyperlipidemia, hypertension, and depression.Results: Even after adjustment for hyperlipidemia, hypertension, depression, body mass index, and other risk factors, the prevalence of heart diseases among those who never or almost never laughed was 1.21 (95% CI, −1.03–1.41) times higher than those who reported laughing every day. The adjusted prevalence ratio for stroke was 1.60 (95% CI, 1.24–2.06).Conclusions: Daily frequency of laughter is associated with lower prevalence of cardiovascular diseases. The association could not be explained by confounding factors, such as depressive symptoms.

著者

Kei Hayashi Ichiro Kawachi Tetsuya Ohira Katsunori Kondo Kokoro Shirai Naoki Kondo

出版者

日本疫学会

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20150196, (Released:2016-03-12)

参考文献数

32

被引用文献数

41

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Background: We sought to evaluate the associations between frequency of daily laughter with heart disease and stroke among community-dwelling older Japanese women and men.Methods: We analyzed cross-sectional data in 20 934 individuals (10 206 men and 10 728 women) aged 65 years or older, who participated in the Japan Gerontological Evaluation Study in 2013. In the mail-in survey, participants provided information on daily frequency of laughter, as well as body mass index, demographic and lifestyle factors, and diagnoses of cardiovascular disease, hyperlipidemia, hypertension, and depression.Results: Even after adjustment for hyperlipidemia, hypertension, depression, body mass index, and other risk factors, the prevalence of heart diseases among those who never or almost never laughed was 1.21 (95% CI, −1.03–1.41) times higher than those who reported laughing every day. The adjusted prevalence ratio for stroke was 1.60 (95% CI, 1.24–2.06).Conclusions: Daily frequency of laughter is associated with lower prevalence of cardiovascular diseases. The association could not be explained by confounding factors, such as depressive symptoms.

著者

Kei Hayashi

出版者

The Japan Society of Applied Physics

雑誌

JSAP Review (ISSN:24370061)

巻号頁・発行日

vol.2022, pp.220403, 2022 (Released:2022-07-29)

参考文献数

37

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Thermoelectric (TE) power generation, a potential clean power technology, has attracted significant attention owing to the recent development of high-performance TE materials. We focused on Mg2Sn and aimed to improve its TE performance by preparing single crystals (SCs) and introducing lattice defects. In this paper, experimental results on crystal structure analysis, microstructures, and TE properties are presented. It is demonstrated that the TE performance of Mg2Sn SCs can be superior to that of Mg2Sn polycrystals via lattice-defect engineering.

著者

Tatsunori MASATANI Masahito ASADA Madoka ICHIKAWA-SEKI Miho USUI Mohamad A. TERKAWI Kei HAYASHI Shin-ichiro KAWAZU Xuenan XUAN

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.13-0274, (Released:2013-09-11)

被引用文献数

4 8

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Peroxiredoxins (Prxs) are a family of antioxidant enzymes. Here, we cloned a 2-Cys Prx, BgTPx-1, from the canine Babesia parasite B. gibsoni. Sequence identity between BgTPx-1 and 2-Cys Prx of B. bovis was 81% at the amino acid level. Enzyme activity assay by using recombinant BgTPx-1 (rBgTPx-1) indicated that BgTPx-1 has antioxidant activity. Antiserum from a mouse immunized with rBgTPx-1 reacted with parasite lysates and detect a protein with a monomeric size of 22 kDa and also a 44 kDa protein, which might be an inefficiently reduced dimer. BgTPx-1 was expressed in the cytoplasm of B. gibsoni merozoites. These results suggest that the BgTPx-1 may play a role to control redox balance in the cytoplasm of B. gibsoni.

著者

Kei Hayashi Shun Yoshioka Toshiaki Chiba Yuzuru Miyazaki

雑誌

Materials Research Meeting 2021

巻号頁・発行日

2021-09-29

著者

Yuzuru Miyazaki Hiroki Nagai Haruki Hamada Yuta Kikuchi Kei Hayashi

雑誌

Materials Research Meeting 2021

巻号頁・発行日

2021-09-29