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14 0 0 0 OA Age-specific Mortality Associated with COVID-19 and Seasonal Influenza in Japan: Using Multiple Population-based Databases

著者
Tatsuya Noda Yasuyuki Okumura Keiko Kan-o Toshibumi Taniguchi Sadao Suzuki Tomoaki Imamura
出版者
Society for Clinical Epidemiology
雑誌
Annals of Clinical Epidemiology (ISSN:24344338)
巻号頁・発行日
vol.4, no.4, pp.129-132, 2022 (Released:2022-10-03)
参考文献数
12
被引用文献数
2

5 0 0 0 OA Age-specific mortality associated with COVID-19 and seasonal influenza in Japan: using multiple population-based databases

著者
Tatsuya Noda Yasuyuki Okumura Keiko Kan-o Toshibumi Taniguchi Sadao Suzuki Tomoaki Imamura
出版者
Society for Clinical Epidemiology
雑誌
Annals of Clinical Epidemiology (ISSN:24344338)
巻号頁・発行日
pp.22016, (Released:2022-08-03)
被引用文献数
2

1 0 0 0 OA Risks of dementia in a general Japanese older population with preserved ratio impaired spirometry: The Hisayama Study

著者
Kenji Kawatoko Yasuyoshi Washio Tomoyuki Ohara Satoru Fukuyama Takanori Honda Jun Hata Taro Nakazawa Keiko Kan-o Hiromasa Inoue Koichiro Matsumoto Tomohiro Nakao Takanari Kitazono Isamu Okamoto Toshiharu Ninomiya
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
pp.JE20230207, (Released:2023-12-02)
参考文献数
48
Background: Studies on the association between preserved ratio impaired spirometry (PRISm) and dementia are limited. Indeed, PRISm has often been overlooked or ignored as an index of lung function impairment. Therefore, we investigated the association of PRISm with the risk for the development of dementia in an older Japanese population.Methods: A total of 1202 community-dwelling, older Japanese participants aged ≥65 years without dementia were followed up for a median of 5.0 years. Participants were categorized by spirometry as follows: normal spirometry (FEV1/FVC ≥0.70 and FEV1 ≥80% predicted), PRISm (≥0.70 and <80%), airflow limitation (AFL) Global Initiative for Chronic Obstructive Lung Disease (GOLD) 1 (<0.70 and ≥80%), and AFL GOLD 2 to 4 (<0.70 and <80%). Hazard ratios (HRs) and their 95% confidence intervals (CIs) were computed using a Cox proportional hazards model.Results: During the follow-up period, 122 participants developed dementia. The age- and sex-adjusted incidences of dementia in the participants with normal spirometry, PRISm, AFL GOLD 1, and AFL GOLD 2 to 4 were 20.5, 37.0, 18.4, and 28.6 per 1000 person-years, respectively. Participants with PRISm had a higher risk of dementia (HR 2.04 [95%CI, 1.19-3.49]) than those with normal spirometry after adjusting for confounders. Moreover, both reduced FEV1% predicted values and FVC% predicted values were associated with the risk for dementia.Conclusion: PRISm was associated with an increased risk of dementia in a general older Japanese population.