- 著者
- Yoshihisa KOJIMA Yoshinosuke HAMADA Naomasa KAWAGUCHI Seiji MORI Kiyoshi DAITO Ayako UCHINAKA Naoya HAYAKAWA Kenji ARITA Yoshitaka NAGASE Nariaki MATSUURA
- 出版者
- Nano Biomedical Society
- 雑誌
- Nano Biomedicine (ISSN:18835198)
- 巻号頁・発行日
- vol.6, no.1, pp.12-20, 2014 (Released:2014-08-24)
- 参考文献数
- 35
We examined the neurological and pathological effects of moxibustion on body temperature in the rat by using in vivo physiological and pathological approaches. To mimic direct and indirect moxibustion, the forelimb skin of rats was stimulated by heat at 80 or 40°C. Heat at 40°C evoked rapid increases in rectal temperature and heart rate. Surgical and chemical sympathectomy antagonized these effects. In contrast, heat at 80°C evoked slow increases in rectal temperature and heart rate, as well as in blood tumor necrosis factor-α and interleukin-6. Although the concentrations of these pyrogens increased significantly, surgical and chemical sympathectomy antagonized these effects. Collectively these data demonstrate that moxibustion may increase body core temperature mainly through sympathetic nerve stimulation, and that low-temperature stimulation is more effective than high-temperature treatment. Therefore, indirect moxibustion or moxibustion at low temperature is safer than direct moxibustion.
- 著者
- Kenji ARITA Aimi YAMAMOTO Yukari SHINONAGA Keiko HARADA Yoko ABE Keizo NAKAGAWA Shigeru SUGIYAMA
- 出版者
- The Japanese Society for Dental Materials and Devices
- 雑誌
- Dental Materials Journal (ISSN:02874547)
- 巻号頁・発行日
- vol.30, no.5, pp.672-683, 2011 (Released:2011-10-08)
- 参考文献数
- 39
- 被引用文献数
- 40 56
The aims of this study were to improve the mechanical and chemical properties of conventional restorative glass ionomer cement (GIC) by adding hydroxyapatite (HAp) preparations with different characteristics, and to investigate the underlying reaction mechanisms. Fuji IX GP® was used as the control GIC. The experimental GICs consisted of four HAp-particles with different characteristics added at 8 mass% to Fuji IX-powder. All cements were prepared by mixing with Fuji IX-liquid (P/L=3.6). Four HAp-particles were analyzed, and then the mechanical strengths and the fluoride-ion- release-recharge-behaviors of five GIC groups were evaluated. The results of this study demonstrate that the addition of HAp particles with highly reactive properties such as high specific surface area can enhance the flexural strength and fluoride ion release properties of conventional restorative GIC. Our results further indicate that HAp functions as an adsorbent and an ion exchangeable agent, resulting in improved mechanical and chemical properties of GIC.