著者
佐伯 弘治 Koji Saeki
雑誌
東京医科大学雑誌 (ISSN:00408905)
巻号頁・発行日
vol.62, no.5, pp.497-498, 2004-09-25
著者
Yui SUZUKI Katsumi TAKABA Itaru YAMAGUCHI Kensuke MYOUJOU Naoya KIMOTO Hisashi IKEGAMI Koji SAEKI Minami IMAIZUMI Chie TAKADA
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.74, no.1, pp.89-92, 2012 (Released:2012-02-01)
参考文献数
14
被引用文献数
4 5

A 15-month-old male beagle dog used in a toxicity study had a primary renal mesenchymal tumor. Macroscopically, the tumor was a gray-white mass which was found in the right kidney, and extended from the capsule to a position slightly compressing the medulla. Microscopically, most of the tumor cells showed a myxoid pattern, in which the matrix was positive for alcian blue staining. In the other parts of the tumor, a fascicular and wavy pattern was observed, and the matrix was full of collagen fibrils. Immunohistochemically, tumor cells were positive for vimentin and fibronectin, and negative for cytokeratin, desmin, á-smooth muscle actin, Von Willebrand factor, cyclooxigenase-2 and myelin basic protein. As a result, we diagnosed this case to be a renal mesenchymal tumor. Based on the microscopic findings, interstitial characteristics and immunohistochemical features, the present case was classified as a congenital mesoblastic tumor.