- 著者
- Hideki WAKUI Ikuko TADA Yasunori KIMURA Kosaku YOSHIDA Yasuyuki ENDO Akira B MIURA
- 出版者
- The Japanese Society of Internal Medicine
- 雑誌
- Japanese Journal of Medicine (ISSN:00215120)
- 巻号頁・発行日
- vol.28, no.6, pp.736-739, 1989 (Released:2006-03-27)
- 参考文献数
- 11
- 被引用文献数
- 1 2
We report an Rh(D)-negative man with myelodysplastic syndrome who produced six anti-erythrocyte alloantibodies (anti-D, -C, -E, -Dia, -Jka and -S) in succession. Three of these antibodies (anti-E, -Jka and -S) were not noted until delayed hemolytic transfusion reactions occurred. Treatment with cortico-steroids was effective in preventing both further formations of antibodies and other transfusion reactions. It was very difficult to find blood compatible with the patient, but repetitive blood transfusions were required for his progressive anemia and thrombocytopenia. Several problems concerning the transfusion of blood in such a case are discussed.