著者

MARIA KOWALSKA

出版者

Journal of Radiation Research Editorial Committee

雑誌

Journal of Radiation Research (ISSN:04493060)

巻号頁・発行日

vol.26, no.1, pp.99-108, 1985-03-15 (Released:2006-06-16)

参考文献数

18

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Three generations of rats were long-term exposed to HTO in drinking water at activity of 37.0 kBq/ ml or to food containing OBT at activity of 48.1 kBq/g. The rats consumed tritiated water and tritiated food ad libitum. The parent females P0 were exposed for 64 days, the F1 and F2 generations were lifetime exposed and F3 generation during whole intrauterine life. It was found that the amount of tritium incorporated into rat brain protein amino acids after administration of tritiated food was higher than after administration of tritiated water and was the highest in rats exposed during their intrauterine life.

著者

MARIA KOWALSKA

出版者

Journal of Radiation Research Editorial Committee

雑誌

Journal of Radiation Research (ISSN:04493060)

巻号頁・発行日

vol.26, no.4, pp.385-394, 1985-12-15 (Released:2006-06-16)

参考文献数

15

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Three generations of rats were long-term exposed to HTO in drinking water at activity of 37.0 kBq/ml or to food containing OBT at activity of 48.1 kBq/g. The rats consumed tritiated water and tritiated food ad libitum. In the experiment the F1 and F2 generation of rats were exposed continuously from conception to the 21-st or 120-th day of age and rats of F3 generation during 22 days of their intrauterine life. It was found that the amount of tritium incorporated into the major rat brain phospholipids and gangliosides after administration of tritiated food was higher than after administration of tritiated water. Tritium activity in all studied phospholipids and gangliosides was the highest in 21-day-old rats exposed during both-pregnancy and lactation.