149 0 0 0 OA Incorporation of Tritiated Water (HTO) or Organically Bound Tritium (OBT) into Amino Acids of Rat Brain Proteins
- 著者
- MARIA KOWALSKA
- 出版者
- Journal of Radiation Research Editorial Committee
- 雑誌
- Journal of Radiation Research (ISSN:04493060)
- 巻号頁・発行日
- vol.26, no.1, pp.99-108, 1985-03-15 (Released:2006-06-16)
- 参考文献数
- 18
Three generations of rats were long-term exposed to HTO in drinking water at activity of 37.0 kBq/ ml or to food containing OBT at activity of 48.1 kBq/g. The rats consumed tritiated water and tritiated food ad libitum. The parent females P0 were exposed for 64 days, the F1 and F2 generations were lifetime exposed and F3 generation during whole intrauterine life. It was found that the amount of tritium incorporated into rat brain protein amino acids after administration of tritiated food was higher than after administration of tritiated water and was the highest in rats exposed during their intrauterine life.
言及状況
外部データベース (DOI)
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トリチウムは脳に蓄積される。
脳のタンパク質のアミノ酸に結合してしまうからだ。