- 著者
- Yoshihito Nihei Monami Kishi Hitoshi Suzuki Ayako Koizumi Maiko Yoshida Sho Hamaguchi Masako Iwasaki Hiromitsu Fukuda Hisatsugu Takahara Masao Kihara Shigeki Tomita Yusuke Suzuki
- 出版者
- The Japanese Society of Internal Medicine
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.61, no.7, pp.1033-1037, 2022-04-01 (Released:2022-04-01)
- 参考文献数
- 19
- 被引用文献数
- 15
A 28-year-old woman experienced gross hematuria after the administration of the second dose of an messenger ribonucleic acid (mRNA) vaccine (BNT162b2). She was diagnosed with Immunogloblin A nephropathy (IgAN) by a renal biopsy two weeks after vaccination, which revealed a mild increase in mesangial cells and a matrix with co-depositions of galactose-deficient IgA1 and C3 in the mesangial region. The gross hematuria and proteinuria gradually improved without any medication, suggesting that immune activation by the mRNA vaccine may not elicit continuous disease progression of IgAN. Thus, further studies investigating the relationship between mRNA vaccines against COVID-19 and the progression of IgAN should be conducted.
- 著者
- Yoshihito Nihei Monami Kishi Hitoshi Suzuki Ayako Koizumi Maiko Yoshida Sho Hamaguchi Masako Iwasaki Hiromitsu Fukuda Hisatsugu Takahara Masao Kihara Shigeki Tomita Yusuke Suzuki
- 出版者
- The Japanese Society of Internal Medicine
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- pp.8787-21, (Released:2022-02-01)
- 参考文献数
- 19
- 被引用文献数
- 15
A 28-year-old woman experienced gross hematuria after the administration of the second dose of an mRNA vaccine (BNT162b2). She was diagnosed with IgA nephropathy (IgAN) by a renal biopsy two weeks after vaccination, which revealed a mild increase in mesangial cells and a matrix with co-depositions of galactose-deficient IgA1 and C3 in the mesangial region. The gross hematuria and proteinuria gradually improved without any medication, suggesting that immune activation by the mRNA vaccine may not elicit continuous disease progression of IgAN. Thus, further studies investigating the relationship between mRNA vaccines against COVID-19 and the progression of IgAN should be conducted.
- 著者
- Yongtae KO Naoto TSUJII Yuichi TAKASE Akira EJIRI Osamu WATANABE Hibiki YAMAZAKI Kotaro IWASAKI Peng YI James H.P. RICE Yuki OSAWA Takuma WAKATSUKI Maiko YOSHIDA Hajime URANO
- 出版者
- The Japan Society of Plasma Science and Nuclear Fusion Research
- 雑誌
- Plasma and Fusion Research (ISSN:18806821)
- 巻号頁・発行日
- vol.16, pp.1402056, 2021-04-21 (Released:2021-05-12)
- 参考文献数
- 20
- 被引用文献数
- 5
We investigated electron cyclotron (EC) wave assisted low voltage Ohmic start-up in the conventional field null configuration (FNC) and the trapped-particle configuration (TPC) in the TST-2 spherical tokamak device. The upper pressure limit for successful burn-through increased when EC power was applied for both the FNC and TPC. On the other hand, at low prefill pressure, breakdown was delayed in the FNC start-up. The achievable plasma current also decreased especially at high EC power. By applying the TPC, fast breakdown was recovered even at high EC power. The plasma current ramp-up rate was also greater with TPC compared with FNC at the same loop voltage waveform. The lower prefill pressure limit for successful breakdown expanded in the TPC compared to that in the FNC. The higher vertical field decay index resulted in faster EC breakdown. The reduction of the upper pressure limit due to impurities was the same in the FNC and TPC indicating that the poloidal field configuration did not significantly affect the upper pressure limit for successful burn-through.