- 著者
- Taiji Ogawa Mariko Honda-Ogawa Kazunori Ikebe Shigetada Kawabata Yoshinobu Maeda
- 出版者
- Nihon University School of Dentistry
- 雑誌
- Journal of Oral Science (ISSN:13434934)
- 巻号頁・発行日
- vol.59, no.3, pp.391-395, 2017 (Released:2017-09-14)
- 参考文献数
- 13
- 被引用文献数
- 1 3
Dry mouth occurs frequently in aged individuals, as well as in patients who are hospitalized, receiving multiple drugs, undergoing radiation treatment to the head and neck, or wearing a removable denture prosthesis, use of mouth rinse being often an option for relief. In the present study, we performed microbiological assessments of subjects given three different commercially available mouth rinses commonly employed in clinical practice (Peptisal, Biotène, ConCool) to determine their effects. For bacterial clearance in vitro, Peptisal showed the highest level of suppression of oral indigenous bacteria found in both planktonic formations and biofilm. Furthermore, the inhibitory effects of these agents on biofilm formation on acrylic resin plates were examined using scanning electron microscopy. Again, Peptisal proved superior, because acquisition of resistance to antimicrobial peptides by a sensitive microbial strain was rarely observed. We conclude that Peptisal is an effective mouth rinse for clearance of planktonic and biofilm microorganisms present in the oral cavity.
- 著者
- Kazuo HARADA Mariko HONDA Kozo NAGASHIMA Satoshi KANISAWA
- 出版者
- Japan Association of Mineralogical Sciences
- 雑誌
- Mineralogical Journal (ISSN:05442540)
- 巻号頁・発行日
- vol.8, no.2, pp.95-109, 1976 (Released:2007-03-31)
- 参考文献数
- 28
- 被引用文献数
- 8 14
A new mineral with the following formula is described: (K1.788Na0.148 Rb0.141)(Li2.536Mn2+0.985Fe2+0.183Fe3+0.061Al1.958Ti0.012) (Si6.646 Al1.354)·O19.634 (F3.159 (OH)1.202)=(K, Na, Rb)2.077(Li, Mn, Fe2+, Fe3+, Al, Ti)5.735(Si, Al)8.000·O19.639 (F, OH)4.361 as OH+O+F=24. It corresponds to manganese analogue of zinnwaldite and is expressed by a K2(Mn2+2−1Li2−3Al2) (Al2−1Si6−7O20) (F2−3 (OH)1−2). The name masutomilite is proposed for the material with Mn2+> Fe2+ in honor of Dr. Kazunosuke Masutomi for his contribution to minerals of Japan.X-ray powder diffraction and optical data indicate the mineral to be monoclinic, space group Cm or C2⁄m with a 5.253(8)Å, b 9.085(4)Å, c 10.108(8)Å, β 100.15(0.03)°, V 474.84(0.56)Å3 and Z=1. The precession method verified the space group. The strongest lines in the X-ray powder pattern are 10.10(72)(001), 3.64(43)(-112), 3.32(100)(003), 3.09(58)(112), 2.903(35)(-113, 031), 2.589(17)(200, -131), 1.989(46)(005), 1.653(23)(204, -135). It is pale purplish pink. Transparent. Cleavage {001} perfect. Hardness (Mohs) 2.5. Sp. Gr. (meas.) 2.94 and 2.96 (calc). Optically biaxial negative with α 1.534, β 1.569, γ 1.570, (−)2V 29°–31°, r>v very weak, X, Z colorless to pale purple, Y purple, absorption X<Z<Y. Optical orientation b=Y, X nearly perpendicular to (001), a∧Z 3°.The mineral occupies core part of a zoned single mica crystal up to 10 cm across and 1 cm thick found in a druse of granite pegmatite at Tanakamiyama, Otsu, Shiga Prefecture, Japan. The outer part of the crystal is a brown manganoan zinnwaldite. The associated minerals are topaz, schorl, albite and quartz.For comparison of a high manganese zinnwaldite with masutomilite, a mica from Tawara, Naégi district, Hirukawa-mura, Gifu Prefecture, Japan is also described.A complete solid solubility does exist for the masutomilite–lepidolite–zinnwaldite series. The relationship between chemical composition, unit-cell dimensions a or b, and optical properties for the masutomilite–lepidolite series is figured out.
- 著者
- Taiji Ogawa Mariko Honda-Ogawa Kazunori Ikebe Yumiko Notomi Yoshiko Iwamoto Itsuki Shirobayashi Seiko Hata Masahito Kibi Shizuko Masayasu Satoshi Sasaki Shigetada Kawabata Yoshinobu Maeda
- 出版者
- 日本大学歯学部
- 雑誌
- Journal of Oral Science (ISSN:13434934)
- 巻号頁・発行日
- pp.16-0722, (Released:2017-10-06)
- 参考文献数
- 31
- 被引用文献数
- 35
Over 700 bacterial species have been detected in the oral cavity. Several studies have suggested that periodontitis is associated with systemic disorders such as diabetes mellitus, indicating a key role for oral microbiota in human health. However, the relationship between oral microbiota and diabetes has not been well clarified. Therefore, we conducted microbiome analysis of saliva samples obtained from 15 elderly residents (3 with type 2 diabetes mellitus [DM] and 12 without diabetes [non-DM]) at three different nursing homes, as well as 9 young healthy controls (HC). Genomic DNA was extracted from each sample, and then the V4 region of the 16S rRNA gene was amplified and sequenced. Alpha diversity, in terms of operational taxonomic unit richness, was significantly higher in samples from the non-DM group than in those from the HC group. Weighted UniFrac distance analysis showed that salivary microbial communities in the DM group were separately clustered. Furthermore, in the DM group, Actinomyces and Selenomonas showed significantly higher abundance, whereas Alloprevotella showed significantly lower abundance, relative to the non-DM group. Although our findings were limited by the small sample size, oral bacterial diversity in the DM group was clearly different from that in the non-DM group.