- 著者
-
Masataka Sato
Satoshi Kodera
Naoto Setoguchi
Kengo Tanabe
Shunichi Kushida
Junji Kanda
Mike Saji
Mamoru Nanasato
Hisataka Maki
Hideo Fujita
Nahoko Kato
Hiroyuki Watanabe
Minami Suzuki
Masao Takahashi
Naoko Sawada
Masao Yamasaki
Shinnosuke Sawano
Susumu Katsushika
Hiroki Shinohara
Norifumi Takeda
Katsuhito Fujiu
Masao Daimon
Hiroshi Akazawa
Hiroyuki Morita
Issei Komuro
- 出版者
- The Japanese Circulation Society
- 雑誌
- Circulation Journal (ISSN:13469843)
- 巻号頁・発行日
- pp.CJ-23-0216, (Released:2023-11-14)
- 参考文献数
- 41
- 被引用文献数
-
2
Background: Left heart abnormalities are risk factors for heart failure. However, echocardiography is not always available. Electrocardiograms (ECGs), which are now available from wearable devices, have the potential to detect these abnormalities. Nevertheless, whether a model can detect left heart abnormalities from single Lead I ECG data remains unclear.Methods and Results: We developed Lead I ECG models to detect low ejection fraction (EF), wall motion abnormality, left ventricular hypertrophy (LVH), left ventricular dilatation, and left atrial dilatation. We used a dataset comprising 229,439 paired sets of ECG and echocardiography data from 8 facilities, and validated the model using external verification with data from 2 facilities. The area under the receiver operating characteristic curves of our model was 0.913 for low EF, 0.832 for wall motion abnormality, 0.797 for LVH, 0.838 for left ventricular dilatation, and 0.802 for left atrial dilatation. In interpretation tests with 12 cardiologists, the accuracy of the model was 78.3% for low EF and 68.3% for LVH. Compared with cardiologists who read the 12-lead ECGs, the model’s performance was superior for LVH and similar for low EF.Conclusions: From a multicenter study dataset, we developed models to predict left heart abnormalities using Lead I on the ECG. The Lead I ECG models show superior or equivalent performance to cardiologists using 12-lead ECGs.